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  1. The local application of triamcinolone acetonide (TA) in patients with macular edema (ME) is off-label and the data are limited. We designed a systematic review and network meta-analysis to compare risk of int...

    Authors: Kexin Liu, Jinyang Yi, Juan Xu, Li Zhong and Na Su
    Citation: BMC Ophthalmology 2025 25:150
  2. The purpose of this study was to report a patient who developed myopic shift and anterior corneal steepening many years following radial keratotomy (RK). The etiology of this myopic shift resulted from central...

    Authors: Ping-Feng Tsai, Ting-Yi Lin, Yu-Min Chang, Ke-Hung Chien, Ming-Cheng Tai and Tzu-Heng Weng
    Citation: BMC Ophthalmology 2025 25:149
  3. Proliferative diabetic retinopathy (PDR) is a serious microvascular complication of diabetes and a leading cause of global vision loss. Pars plana vitrectomy (PPV) is the primary surgical treatment for PDR, bu...

    Authors: Zhi-gang Wang, Ping Li, Xiu-min Yang, Zi-qi Wang and Pei-ran Zhang
    Citation: BMC Ophthalmology 2025 25:148
  4. Pupillary capture can cause complications after intrascleral intraocular lens (IOL) fixation; however, no method has been established to definitively prevent pupillary capture. Therefore, we aimed to examine t...

    Authors: Mayumi Nagata, Hiroyuki Matsushima, Norifumi Chiba and Tadashi Senoo
    Citation: BMC Ophthalmology 2025 25:146
  5. Orthokeratology (Ortho-K) lenses are increasingly used in children to manage myopia by reshaping the cornea and potentially influencing axial length changes. This study investigated factors affecting axial len...

    Authors: Guangbin Zhong, Ruinian Zheng and Linyi Luo
    Citation: BMC Ophthalmology 2025 25:145
  6. Myopia is an increasingly prevalent visual impairment associated with severe ocular complications. Risk factors for childhood myopia include genetics, East Asian ethnicity, age, parental myopia, and various en...

    Authors: Ju-Hsien Li, Ho-Min Chen, Kuan-Wen Su, Yu-Kai Kuo, Cheng-Hsiu Wu, Nan-Ni Chen, Pei-Wei Huang and Chi-Chin Sun
    Citation: BMC Ophthalmology 2025 25:143
  7. To describe the demoFigurey and clinical characteristics of intraocular foreign body as open globe injury type at National Eye Center Cicendo Eye Hospital.

    Authors: Made Indra Widyanatha, Henry Santosa Sungkono, Grimaldi Ihsan, Rova Virgana, Erwin Iskandar and Arief Sjamsulaksan Kartasasmita
    Citation: BMC Ophthalmology 2025 25:142
  8. This study aims to evaluate the effects of epithelial-off corneal cross-linking (CXL) on the ocular surface and corneal topographic and optical parameters in progressive keratoconus (KCN) cases.

    Authors: Nazli Taheri, Afshin Lotfi Sadigh, Salar Abed Nikmanesh, Amir Tarkavani, Peyman Ghodraty, Amin Arasteh and Tahereh Attar Gharamaleki
    Citation: BMC Ophthalmology 2025 25:141
  9. To evaluate differences in clinical outcome, safety, and efficacy of photorefractive keratectomy (PRK) and laser-assisted in situ keratomileusis (LASIK) in the correction of hyperopic refractive errors.

    Authors: Mohammed Naji Almutairi, Abdullrahman M. Alshehri, Abdulrahman Y. Alhoumaily, Osamah Alnahdi, Mohammed A. Taha and Shiji Gangadharan
    Citation: BMC Ophthalmology 2025 25:140
  10. For patients with bilateral age-related cataracts, sequential phacoemulsification and intraocular lens implantation is a common treatment. However, it remains unclear whether surgery on the first eye has an im...

    Authors: Yang Li, Taiying Cheng, Sujun Zhou, Fayuan Li, Wenjun Guo, Mingbo Li and Taixiang Liu
    Citation: BMC Ophthalmology 2025 25:137
  11. Accidental ocular injuries caused by laser devices used in non-medical settings are rare but potentially vision-threatening. This case report describes a 24-year-old woman who sustained a full-thickness macula...

    Authors: Nazanin Zeinali Nezhad, Atiye Moradi, Shiva Pouradeli, Mohammad Rezaei Zadeh Rukerd and Mahdi Sharifzadeh Kermani
    Citation: BMC Ophthalmology 2025 25:135
  12. Acute retinal necrosis triggered by routine cataract surgery is a rare condition, which may be overlooked by the clinicians. We report a case of unilateral acute retinal necrosis (ARN) with the onset 4 days af...

    Authors: Ting Luo, Lu Wang, Li Zhang, Ming-Jue Hu, Si-Rui Zhou, Xing-Yu He and Jun-Feng Yang
    Citation: BMC Ophthalmology 2025 25:131
  13. Conjunctival malignant melanoma is an aggressive tumor with the potential for metastasis and death. It is rare in the black population because of the protective effect of melanin. Metastases are usually to reg...

    Authors: Chigozie C. Okongwu, Bolajoko Abidemi Adewara, Olaejirinde O. Olaofe, Ademola I. Soremekun, Samuel O. Ayodele, Yusuf O. Abdullahi, Ese E. Ewoye and James O. Oladele
    Citation: BMC Ophthalmology 2025 25:130
  14. Sturge-Weber syndrome (SWS) is a rare congenital disorder with diverse manifestations, including diffuse choroidal hemangiomas causing visual impairment. This case report describes a 14-year-old girl with reti...

    Authors: Ting-Wei Su, I-Ling Chou, Huai-Chin Fan, San-Ni Chen and Chin-Nan Chu
    Citation: BMC Ophthalmology 2025 25:129
  15. This response addresses readers’ comments on our study published in BMC Ophthalmology, which analyzed astigmatic variations among Duane Retraction Syndrome (DRS) subtypes. We clarified that our retrospective s...

    Authors: Masoud Khorrami-Nejad, Mohamad Reza Akbari, Babak Masoomian, Hayder Ali Mahmood, Kim Daneshvar and Ali Majdi
    Citation: BMC Ophthalmology 2025 25:128

    The original article was published in BMC Ophthalmology 2025 25:126

  16. A recent article provides valuable insights into different aspects of astigmatism in the Duane Retraction Syndrome (DRS) subtypes. The differing underlying pathophysiology in type II DRS and its higher prevale...

    Authors: Hajar Farvardin and Majid Farvardin
    Citation: BMC Ophthalmology 2025 25:126

    The original article was published in BMC Ophthalmology 2025 25:15

    The Matters Arising to this article has been published in BMC Ophthalmology 2025 25:128

  17. Growth of macular neovascularization (MNV) associated with development of complete retinal pigment epithelial and outer retina atrophy (cRORA) been observed in eyes neovascular age-related macular degeneration...

    Authors: Laurenz Pauleikhoff, Martin Ziegler, Isabel Bachmeier, Siqing Yu, Beatriz Garcia Armendariz and Daniel Pauleikhoff
    Citation: BMC Ophthalmology 2025 25:123
  18. This study aimed to investigate the long-term effects of retinopathy of prematurity (ROP) on visual function and ocular anatomy. We compared biometric values, foveal thickness, and choroidal thickness among ch...

    Authors: Ali Kutay Kılınç, O. Ozdemir, D. E. Acar and M. U. Işık
    Citation: BMC Ophthalmology 2025 25:122
  19. To compare the refractive outcomes and visual quality among different types of astigmatism following SMILE and evaluate effective optical zone (EOZ) features, decentration and their potential effects on visual...

    Authors: Xuyun Meng, Hui Ding, Zhenduo Yang, Xiaodan Chen, Shisi Hu and Xingwu Zhong
    Citation: BMC Ophthalmology 2025 25:121
  20. Pre-diabetes is the preceding condition of diabetes, and in some cases, fundus changes have been seen in pre-diabetes. The inflammatory response is widely recognized as being involved in the pathophysiologic p...

    Authors: Yixun Chen, Yan meng, Mengjia Tan, Jun Ma, Jian Zhu, Min Ji and Huaijin Guan
    Citation: BMC Ophthalmology 2025 25:119
  21. Childhood obesity is a growing public health concern, associated with several systemic disorders including changes in retinal microvasculature. This study aims to assess the relationship between body compositi...

    Authors: Sina Arabi, Mohsen Pourazizi, Motahar Heidari-Beni, Maryam Yazdi and Roya Kelishadi
    Citation: BMC Ophthalmology 2025 25:118
  22. Faricimab is a novel anti-vascular endothelial growth factor agent, used to treat patients with neovascular age-related macular degeneration (nAMD). This study assessed efficacy and safety of faricimab in prev...

    Authors: Maria A. Bantounou, Mohammed Elsheikh, Adelehin Ijasan and Cynthia Santiago
    Citation: BMC Ophthalmology 2025 25:117
  23. The purpose of this study was to clinically and quantitatively evaluate the speed of brain adaptation following multifocal intraocular lens (IOL) implantation. The speed of brain adaptation is considered to va...

    Authors: Yutaro Nishi, Hiroyuki Nishi, Maiko Fukui, Miki Tatsumichi, Kayo Nishi and Okihiro Nishi
    Citation: BMC Ophthalmology 2025 25:116
  24. To explore a novel semi-automatic quantitative method for detecting lid-wiper epitheliopathy (LWE) and analyze its impact on the distribution of corneal epithelial thickness (CET).

    Authors: Jingjian Ye, Meng Lin, Xuzhou Chen, Yuhang Yang, Jue Lin, Di Ma, Ziya Liu and Liang Hu
    Citation: BMC Ophthalmology 2025 25:113
  25. Retinal vein occlusion (RVO) is a significant retinal vascular disorder that has been hypothesized to increase the risk of cerebrovascular accidents (CVA). Given the shared vascular pathology between the retin...

    Authors: Kai-Yang Chen, Hoi-Chun Chan and Chi-Ming Chan
    Citation: BMC Ophthalmology 2025 25:112
  26. Whipple’s disease, caused by Tropheryma whipplei, is a rare chronic infection predominantly affecting the gastrointestinal tract. Ocular involvement is uncommon, and periorbital manifestations are exceedingly ...

    Authors: Ashwaq Yahya Asiri, Khawlah A. Alzaben, Yousef A. AlOtaibi, Humoud Mohammad AlOtaibi and Hind Manaa Alkatan
    Citation: BMC Ophthalmology 2025 25:111
  27. When performing corneal endothelial transplantation, the presence of low intraocular pressure, abnormal host corneal shape, and septal defects between the anterior and posterior chamber may cause poor graft ad...

    Authors: Shin-ichiro Ito, Takahiro Nakamura, Daiki Sakai, Marika Hirota, Chie Sotozono and Yasuo Kurimoto
    Citation: BMC Ophthalmology 2025 25:110
  28. This case report documents a rare instance of intraventricular migration of silicone oil (IVM-SiO), initially misinterpreted as intraventricular hemorrhage on computed tomography (CT), in a patient with a hist...

    Authors: Wenkui Li, Chuyue Wu, Wei Xue and Rong Deng
    Citation: BMC Ophthalmology 2025 25:109
  29. To compare the visual outcomes of simple high myopia (HM) and mild pathologic myopia (PM) following implantation of a trifocal intraocular lens (IOL), and investigate the influence of fundus structures.

    Authors: Meiyi Zhu, Zongsheng Zeng, Wei Fan and Guangbin Zhang
    Citation: BMC Ophthalmology 2025 25:108
  30. Pterygium, abnormal growths of conjunctival tissue onto the cornea, are common ocular surface conditions with a high risk of recurrence after surgery and potential ophthalmic complications. The exact cause of ...

    Authors: Dahee Choi, Ann-Yae Na, Seok-Won Jeoung, Yun-Hee Choi, Nayoon Park, Hyun-Sun Park, Hyuk-Kwon Kwon, Hyun-Shik Lee, Dong-Hyung Cho, Dong Hyun Kim and Hong-Yeoul Ryu
    Citation: BMC Ophthalmology 2025 25:106
  31. The sclera is the target organ of axial elongation during myopia onset and progression. Visualizing the sclera in-vivo is important for monitoring the dynamic changes of the sclera remodeling in experimental m...

    Authors: Ruiheng Zhang, Chuyao Yu, Li Dong, Yitong Li, Xuhan Shi, Haotian Wu, Wenda Zhou, Heyan Li and Wenbin Wei
    Citation: BMC Ophthalmology 2025 25:105
  32. During accommodation, the eye undergoes significant structural changes, altering wavefront aberrations. So, this study aimed to evaluate changes in Zernike coefficients up to the 6th order with different accom...

    Authors: María Mechó-García, María Arcas-Carbonell, Elvira Orduna-Hospital, Ana Sánchez-Cano, Vicente Fernández-Sánchez, Rute J. Macedo-de-Araújo, Paulo Fernandes, José Manuel González-Méijome and Jos J. Rozema
    Citation: BMC Ophthalmology 2025 25:104
  33. To determine if a standardised Toric Allocation Pathway (TAP) improved visual and refractive outcomes for patients undergoing cataract surgery at a tertiary referral teaching hospital.

    Authors: Muhammad Azaan Khan, Dominic McCall and Chameen Samarawickrama
    Citation: BMC Ophthalmology 2025 25:102

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