From: Unveiling the levels and significance of different serpin family proteins in aqueous humor dynamics
 |  | Overall | Cataract | POAG | |||
---|---|---|---|---|---|---|---|
Serpins | Clinical Variables | Corr. | P-value | Corr. | P-value | Corr. | P-value |
OCT Parameters | |||||||
SERPINA4 | Avg. RNFL Thickness | 0.21 | < 0.01* | 0.12 | 0.12 | 0.07 | 0.61 |
SERPINA4 | Inferior Thickness | 0.22 | < 0.01* | 0.14 | 0.08 | 0.11 | 0.42 |
SERPINA4 | Nasal Thickness | 0.15 | 0.02* | 0.06 | 0.47 | 0.11 | 0.41 |
SERPINA4 | Superior Thickness | 0.14 | 0.04* | 0.03 | 0.74 | 0.02 | 0.91 |
SERPINA4 | Temporal Thickness | 0.20 | < 0.01* | 0.18 | 0.02* | -0.02 | 0.88 |
SERPINI1 | Avg. RNFL Thickness | 0.33 | < 0.01* | 0.12 | 0.12 | 0.35 | 0.01* |
SERPINI1 | Inferior Thickness | 0.33 | < 0.01* | 0.14 | 0.07 | 0.33 | 0.01* |
SERPINI1 | Nasal Thickness | 0.25 | < 0.01* | 0.11 | 0.17 | 0.27 | 0.04* |
SERPINI1 | Superior Thickness | 0.32 | < 0.01* | 0.13 | 0.10 | 0.36 | < 0.01* |
SERPINI1 | Temporal Thickness | 0.13 | 0.049* | -0.09 | 0.26 | 0.19 | 0.14 |
SERPINA6 | Inferior Thickness | 0.14 | 0.04* | -0.05 | 0.53 | -0.02 | 0.90 |
SERPINA6 | Temporal Thickness | 0.19 | < 0.01* | 0.17 | 0.03* | -0.04 | 0.77 |
SERPINA3 | Temporal Thickness | 0.06 | 0.36 | 0.20 | 0.01* | -0.07 | 0.59 |
SERPINA7 | Temporal Thickness | 0.15 | 0.02* | 0.11 | 0.15 | 0.09 | 0.51 |
SERPINC1 | Temporal Thickness | 0.14 | 0.04* | 0.12 | 0.14 | 0.01 | 0.95 |
SERPINF2 | Temporal Thickness | 0.08 | 0.23 | 0.18 | 0.02* | -0.16 | 0.23 |
HRT Parameters | |||||||
SERPINA4 | Height Variability of Contour (mm) | 0.05 | 0.53 | -0.20 | 0.02* | 0.21 | 0.18 |
SERPINA4 | Linear Cup to Disk Ratio | 0.06 | 0.38 | 0.21 | 0.01* | 0.03 | 0.84 |
SERPINA4 | Max Cup Depth (mm) | -0.09 | 0.24 | -0.20 | 0.03* | 0.14 | 0.43 |
SERPINI1 | Cup to Disc Area Ratio | -0.16 | 0.04* | -0.06 | 0.51 | -0.28 | 0.08 |
SERPINI1 | Linear Cup to Disk Ratio | 0.00 | 0.99 | 0.26 | < 0.01* | -0.17 | 0.19 |
SERPINI1 | Rim Area (mm2) | 0.17 | 0.02* | 0.05 | 0.59 | 0.29 | 0.06 |
SERPINI1 | Rim Volume (mm3) | 0.18 | 0.02* | 0.02 | 0.87 | 0.35 | 0.02* |
SERPINC1 | Disc Area (mm2) | -0.10 | 0.21 | -0.22 | 0.01* | 0.05 | 0.78 |
SERPINC1 | Rim Area (mm2) | -0.06 | 0.43 | -0.21 | 0.02* | -0.08 | 0.61 |
SERPINA5 | Cup Area (mm2) | 0.16 | 0.04* | 0.10 | 0.28 | 0.22 | 0.22 |
SERPINA6 | Linear Cup to Disk Ratio | 0.09 | 0.16 | 0.25 | < 0.01* | 0.14 | 0.28 |
SERPINF2 | Cup Area (mm2) | -0.10 | 0.20 | -0.18 | 0.04* | 0.03 | 0.87 |
SERPINA4 | Reinhard O. W. Burk (RB) discriminant function value | 0.06 | 0.44 | -0.04 | 0.62 | 0.35 | 0.04* |
SERPINA5 | Reinhard O. W. Burk (RB) discriminant function value. | -0.19 | 0.01* | -0.12 | 0.19 | -0.34 | 0.05 |
SERPING1 | Reinhard O. W. Burk (RB) discriminant function value | -0.02 | 0.85 | -0.25 | < 0.01* | 0.00 | 0.98 |
Other Parameters | |||||||
SERPINA7 | IOP | -0.14 | 0.02* | -0.16 | 0.03* | -0.14 | 0.24 |