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Table 4 Serpins significantly correlated with clinical parameters

From: Unveiling the levels and significance of different serpin family proteins in aqueous humor dynamics

  

Overall

Cataract

POAG

Serpins

Clinical Variables

Corr.

P-value

Corr.

P-value

Corr.

P-value

OCT Parameters

SERPINA4

Avg. RNFL Thickness

0.21

< 0.01*

0.12

0.12

0.07

0.61

SERPINA4

Inferior Thickness

0.22

< 0.01*

0.14

0.08

0.11

0.42

SERPINA4

Nasal Thickness

0.15

0.02*

0.06

0.47

0.11

0.41

SERPINA4

Superior Thickness

0.14

0.04*

0.03

0.74

0.02

0.91

SERPINA4

Temporal Thickness

0.20

< 0.01*

0.18

0.02*

-0.02

0.88

SERPINI1

Avg. RNFL Thickness

0.33

< 0.01*

0.12

0.12

0.35

0.01*

SERPINI1

Inferior Thickness

0.33

< 0.01*

0.14

0.07

0.33

0.01*

SERPINI1

Nasal Thickness

0.25

< 0.01*

0.11

0.17

0.27

0.04*

SERPINI1

Superior Thickness

0.32

< 0.01*

0.13

0.10

0.36

< 0.01*

SERPINI1

Temporal Thickness

0.13

0.049*

-0.09

0.26

0.19

0.14

SERPINA6

Inferior Thickness

0.14

0.04*

-0.05

0.53

-0.02

0.90

SERPINA6

Temporal Thickness

0.19

< 0.01*

0.17

0.03*

-0.04

0.77

SERPINA3

Temporal Thickness

0.06

0.36

0.20

0.01*

-0.07

0.59

SERPINA7

Temporal Thickness

0.15

0.02*

0.11

0.15

0.09

0.51

SERPINC1

Temporal Thickness

0.14

0.04*

0.12

0.14

0.01

0.95

SERPINF2

Temporal Thickness

0.08

0.23

0.18

0.02*

-0.16

0.23

HRT Parameters

SERPINA4

Height Variability of Contour (mm)

0.05

0.53

-0.20

0.02*

0.21

0.18

SERPINA4

Linear Cup to Disk Ratio

0.06

0.38

0.21

0.01*

0.03

0.84

SERPINA4

Max Cup Depth (mm)

-0.09

0.24

-0.20

0.03*

0.14

0.43

SERPINI1

Cup to Disc Area Ratio

-0.16

0.04*

-0.06

0.51

-0.28

0.08

SERPINI1

Linear Cup to Disk Ratio

0.00

0.99

0.26

< 0.01*

-0.17

0.19

SERPINI1

Rim Area (mm2)

0.17

0.02*

0.05

0.59

0.29

0.06

SERPINI1

Rim Volume (mm3)

0.18

0.02*

0.02

0.87

0.35

0.02*

SERPINC1

Disc Area (mm2)

-0.10

0.21

-0.22

0.01*

0.05

0.78

SERPINC1

Rim Area (mm2)

-0.06

0.43

-0.21

0.02*

-0.08

0.61

SERPINA5

Cup Area (mm2)

0.16

0.04*

0.10

0.28

0.22

0.22

SERPINA6

Linear Cup to Disk Ratio

0.09

0.16

0.25

< 0.01*

0.14

0.28

SERPINF2

Cup Area (mm2)

-0.10

0.20

-0.18

0.04*

0.03

0.87

SERPINA4

Reinhard O. W. Burk (RB) discriminant function value

0.06

0.44

-0.04

0.62

0.35

0.04*

SERPINA5

Reinhard O. W. Burk (RB) discriminant function value.

-0.19

0.01*

-0.12

0.19

-0.34

0.05

SERPING1

Reinhard O. W. Burk (RB) discriminant function value

-0.02

0.85

-0.25

< 0.01*

0.00

0.98

Other Parameters

SERPINA7

IOP

-0.14

0.02*

-0.16

0.03*

-0.14

0.24

  1. Corr.: Correlation coefficient; * adj. p-value < 0.05