Unveiling the levels and significance of different serpin family proteins in aqueous humor dynamics

BMC Ophthalmology

Table 2 Baseline sex- and race- specific differences in the levels of SERPINs in subjects with cataracts

Gene symbol	Female PSM ± SEM	Male PSM ± SEM	Female vs. Male FC	P-value	African American PSM ± SEM	Caucasian PSM ± SEM	African American vs. Caucasian FC	P-value
SERPINA1	20,032.34 ± 488.82	23,020.18 ± 609.20	0.87	< 0.01*	19,070.11 ± 488.16	23,961.17 ± 528.56	0.80	< 0.01*
SERPINF1	13,949.09 ± 327.15	12,180.97 ± 415.89	1.15	< 0.01*	12,593.88 ± 406.01	14,084.66 ± 313.06	0.89	< 0.01*
SERPINC1	4,953.03 ± 142.24	5,570.34 ± 184.12	0.89	0.01*	4,863.35 ± 152.06	5,642.39 ± 168.95	0.86	< 0.01*
SERPINA3	3,974.53 ± 110.39	4,262.68 ± 165.20	0.93	0.15	4,097.94 ± 138.72	4,091.37 ± 127.71	1.00	0.97
SERPING1	2,965.06 ± 62.59	2,814.05 ± 73.37	1.05	0.12	2,997.38 ± 68.39	2,840.34 ± 66.38	1.06	0.10
AGT	2,215.49 ± 63.00	2,346.00 ± 84.78	0.94	0.22	2,221.69 ± 68.62	2,319.16 ± 78.91	0.96	0.35
SERPINF2	575.96 ± 45.09	787.33 ± 63.25	0.73	0.01*	656.00 ± 55.12	666.74 ± 52.05	0.98	0.89
SERPINA4	377.05 ± 31.42	491.17 ± 39.32	0.77	0.02*	421.73 ± 37.34	413.80 ± 32.90	1.02	0.87
SERPINA6	341.68 ± 20.64	382.89 ± 29.90	0.89	0.26	346.45 ± 25.42	366.60 ± 23.60	0.95	0.56
SERPIND1	242.31 ± 27.15	381.55 ± 47.55	0.64	0.01*	366.31 ± 41.07	218.43 ± 25.07	1.68	< 0.01*
SERPINI1	242.88 ± 16.49	228.71 ± 19.32	1.06	0.58	251.65 ± 18.54	218.62 ± 17.10	1.15	0.19
SERPINA7	172.40 ± 17.38	215.93 ± 22.72	0.80	0.13	199.18 ± 20.88	179.27 ± 18.53	1.11	0.48
SERPINA5	92.76 ± 9.98	93.76 ± 12.13	0.99	0.95	102.82 ± 12.01	82.84 ± 9.30	1.24	0.19

ISSN: 1471-2415