Fig. 4
From: Orbital mesenchymal chondrosarcoma and its specific fusion gene HEY1-NCOA2

Case 4. (a and b) MRI before first surgery shows a circular-like isointense lesion with a size of 1.4Â cm Ă— 1.5Â cm located in the superior temporal area of the muscle cone behind the eyeball, compressing the optic nerve in the axial scan of the orbit on T1- and T2-weighted images. (c) MRI before first surgery shows nonhomogeneous enhancement of the lesion in the axial and coronal scan of the T2-weighted image. (d) MRI before first surgery shows a circular-like lesion located in the superior temporal area of the muscle cone behind the eyeball in the sagittal scan of the T1-weighted image. (e and f) CDU before first and second surgeries show the irregular isoechoic to hyperechoic mass with well-defined border behind the eyeball, and the optic nerve is compressed to displace to the nasal temporal area at the time of the relapse. (g and h) Histopathology show a large percentage of undifferentiated mesenchymal cells, which were elliptical or short shuttle in first specimen, and stratified distribution in the recurrent specimen (Ă—20), yellow\(\:\to\:\), undifferentiated mesenchymal round cells; yellow\(\:\to\:\), areas of immature cartilage; (i) CT image of 8 months after the second surgery, axial scan of the orbit on soft tissue window, and slight thickening of soft tissue in the temporal aspect of the left orbit