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Table 3 Association between HbA1 C and DR, stratified by Sex, age, ACR30, Ischaemic Heart Disease and stroke

From: Inverted U-shaped relationship between HbA1c and diabetic retinopathy in diabetic patients: a cross-sectional study

 

Model 1

[OR (95% CI), P]

Model 2

[OR (95% CI), P]

Model 3

[OR (95% CI), P]

Stratified by Sex

   

 Male

1.08 (1.01, 1.17),0.0329

1.11 (1.03, 1.20), 0.0074

1.16 (1.04, 1.28), 0.0049

 Female

1.04 (0.96, 1.13),0.2947

1.07 (0.99, 1.16), 0.1082

1.11 (0.99, 1.24), 0.0640

Stratified by Age

   

 19.8–59.5 years

1.05 (0.96, 1.14), 0.3165

1.05 (0.96, 1.14), 0.3147

1.09 (0.96, 1.24), 0.1816

 59.6–69.8 years

1.07 (0.97, 1.18), 0.2046

1.07 (0.97, 1.18), 0.1961

1.07 (0.94, 1.22), 0.3040

 69.9–96.4 years

1.16 (1.04, 1.29), 0.0093

1.16 (1.04, 1.29), 0.0088

1.29 (1.12, 1.49), 0.0004

Stratified by ACR30

   

 No

1.00 (0.93, 1.08), 0.9996

1.00 (0.93, 1.08), 0.9848

1.03 (0.93, 1.14), 0.5544

 Yes

1.10 (1.01, 1.19), 0.0348

1.09 (1.00, 1.19), 0.0438

1.24 (1.10, 1.40), 0.0004

Stratified by Ischaemic Heart Disease

   

 No

1.05 (0.99, 1.11), 0.1331

1.05 (0.99, 1.11), 0.1322

1.11 (1.03, 1.20), 0.0102

 Yes

1.25 (1.06, 1.46), 0.0065

1.25 (1.07, 1.47), 0.0061

1.27 (1.02, 1.58), 0.0015

Stratified by Stroke

   

 Yes

1.10 (0.87, 1.41), 0.4279

1.10 (0.86, 1.40), 0.4677

1.01 (0.71, 1.45), 0.9411

 No

1.06 (1.00, 1.12), 0.0350

1.06 (1.00, 1.12), 0.0352

1.14 (1.05, 1.23), 0.0009

  1. Subgroup analyses stratified by sex, age, ACR30, Ischaemic heart disease and stroke, adjusted for BMI, SBP, DBP, AC, Cholesterol, Triglycerides, LDL, HDL, ACEI and/or ARB use, β-blocker use, Diuretic use, Calcium channel blocker use and ABI were adjusted