Table 3 Comparison of peripapillary perfusion density and vessel density among three groups

Perfusion Density (PD)

 1–3 mm inner (%)

 Average

56.01 ± 10.53

52.16 ± 8.75

47.91 ± 12.95

0.001^*

0.071

<0.001^*

0.046^*

 Superonasal

60.51 ± 16.09

57.24 ± 15.37

54.46 ± 17.27

0.179

 Nasal

53.71 ± 13.55

44.58 ± 13.22

37.90 ± 15.48

<0.001^*

0.001^*

<0.001^*

0.017^*

 Inferonasal

68.38 ± 14.78

65.21 ± 12.36

62.87 ± 16.25

0.166

 Inferotemporal

72.57 ± 14.03

70.46 ± 13.18

65.84 ± 17.08

0.070

 Temporal

40.37 ± 12.87

37.16 ± 12.41

36.38 ± 12.87

0.251

 Superotemporal

54.25 ± 15.60

55.05 ± 15.85

50.50 ± 16.38

0.306

 3–6 mm outer (%)

 Average

42.92 ± 6.70

40.20 ± 7.24

38.13 ± 8.78

0.008^*

0.069

0.002^*

0.168

 Superonasal

47.40 ± 13.01

44.07 ± 13.00

41.35 ± 15.50

0.112

 Nasal

29.27 ± 7.92

27.08 ± 10.69

25.04 ± 9.66

0.090

 Inferonasal

36.52 ± 12.82

35.87 ± 12.90

37.57 ± 13.24

0.799

 Inferotemporal

71.03 ± 10.57

65.47 ± 13.16

65.58 ± 17.22

0.073

 Temporal

38.52 ± 10.58

36.04 ± 12.16

35.35 ± 9.69

0.312

 Superotemporal

60.96 ± 11.95

57.91 ± 12.03

53.19 ± 17.96

0.024^*

0.272

0.007^*

0.091

Vessel density(VD)

 Inner 1–3 mm (mm^− 1)

 Average

15.41 ± 2.68

14.39 ± 2.17

13.55 ± 2.98

0.002^*

0.048

<0.001^*

0.102

 Superonasal

13.69 ± 3.30

13.38 ± 3.42

12.61 ± 3.58

0.268

 Nasal

15.71 ± 3.72

13.00 ± 3.48

11.19 ± 4.36

<0.001^*

<0.001^*

<0.001^*

0.018^*

 Inferonasal

15.76 ± 3.17

15.13 ± 2.49

14.37 ± 3.84

0.096

 Inferotemporal

16.05 ± 3.09

15.53 ± 3.08

15.03 ± 2.57

0.225

 Temporal

15.69 ± 4.22

14.34 ± 4.15

13.74 ± 4.73

0.076

 Superotemporal

15.65 ± 3.95

15.14 ± 3.44

14.45 ± 3.61

0.262

 Outer 3–6 mm (mm^− 1)

 Average

13.74 ± 2.26

12.78 ± 2.53

12.09 ± 2.83

0.006^*

0.057

0.002^*

0.157

 Superonasal

13.40 ± 3.69

12.46 ± 3.79

12.99 ± 3.67

0.665

 Nasal

10.61 ± 3.04

9.62 ± 4.26

9.28 ± 3.71

0.181

 Inferonasal

11.07 ± 4.12

10.44 ± 3.91

10.89 ± 4.13

0.712

 Inferotemporal

18.02 ± 2.56

16.60 ± 3.09

16.23 ± 4.44

0.025^*

0.036^*

0.010^*

0.585

 Temporal

15.45 ± 3.87

14.49 ± 4.48

13.93 ± 4.85

0.223

 Superotemporal

17.84 ± 2.92

16.53 ± 3.31

15.67 ± 6.09

0.044^*

0.122

0.013^*

0.314