From post-war reconstruction to the twenty-first century – ophthalmic pathology in Freiburg 1945–2015: review of 39,256 surgical specimens from various topographical regions collected over 71 years at a large German tertiary eye care centre

Table 19 Comparison of topographical areas

Author	Rohrbach et al. [16]						Spraul and Grossniklaus [17]	Current study
Region	Tübingen						Atlanta	Freiburg
Time period	1900	1920	1940	1960	1980	1990	1941–1995	1945–2015
Number	n = 98	n = 87	n = 239	n = 230	n = 656	n = 525	n = 24,444	n = 39,256
Eyelid	5%	17%	12%	34%	29%	45%	8%	50%
Cornea	0%	1%	3%	16%	23%	22%	37%	16%
Conjunctiva	3%	1%	4%	12%	10%	16%	7%	14%
Eyeball	51%	69%	37%	24%	20%	9%	¹⁾	9.1%
Temporal artery	²⁾	²⁾	²⁾	²⁾	²⁾	²⁾	²⁾	3.9%
Orbit	1%	0%	3%	3%	1%	1%	2%	1.4%
Lens	³⁾	³⁾	³⁾	³⁾	³⁾	³⁾	15%	0.9%
Vitreous	³⁾	³⁾	³⁾	³⁾	³⁾	³⁾	11%	0.5%
Retina	³⁾	³⁾	³⁾	³⁾	³⁾	³⁾	7%	0.3%
Choroidea	³⁾	³⁾	³⁾	³⁾	³⁾	³⁾	9%	0.1%
Other location	38% ⁴⁾	11% ⁴⁾	40% ⁴⁾	10% ⁴⁾	18% ⁴⁾	8% ⁴⁾	3%	3.5% ⁵⁾

Relative frequencies of specimens from various topographical areas during the observation period (1945–2015) and comparison with one other study. Percentages may not total 100 due to rounding
¹⁾ Eyeballs were not evaluated as a single location; individual diagnoses were assigned to the respective localisations (cornea, lens, vitreous, retina, choroidea) [17]
²⁾ Included in “other location” [16, 17]
³⁾ Not specified separately
⁴⁾ Includes intraocular tissue (1900: 16%, 1920: 3%, 1940: 21%, 1960: 4%, 1980: 13%, 1990: 4%), lacrimal duct (1900: 8%, 1920: 6%, 1940: 14%, 1960: 1%, 1980: 1%, 1990: 1%), temporal artery biopsies, gangliectomies (1900) and other unclassifiable and lost tissue samples (1900: 15%, 1920: 2%, 1940: 5%, 1960: 5%, 1980: 4%, 1990: 3%) [16]
⁵⁾ Does not include orbit, lens, vitreous, retina, choroidea

ISSN: 1471-2415