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Table 1 Demographics of the patients. BEB Group data collected are pre-injection data of botulinum toxin

From: Tear film lipid layer thickness and blink dynamics in patients with blepharospasm

 

BEB Group

DES Group

p Value

N (eyes)

28

28

 

Age (mean ± SD, years)

62.2 ± 12.4

64.6 ± 11.7

0.4537*

Male Gender (%)

8 (28.6)

6 (21.4)

0.5371†

with DM (%)

3 (10.7)

3 (10.7)

1.0†

with HBP (%)

10 (35.7)

13 (46.4)

0.4151†

LLT min (mean ± SD, nm)

56.4 ± 27.2

67.2 ± 25.1

0.1280*

LLT max (mean ± SD, nm)

83.4 ± 18.1

83.7 ± 22.2

0.9529*

LLT avg (mean ± SD, nm)

72.4 ± 22.7

76.2 ± 25.4

0.5591*

MG loss (mean ± SD, number)

1.93 ± 1.05

1.70 ± 0.95

0.4103*

BCVA

0.72 ± 0.29

0.66 ± 0.29

0.4966*

IOP (mean ± SD, mmHg)

14.6 ± 2.9

15.3 ± 2.9

0.4034*

Total blink (mean ± SD, times/20 s)

7.71 ± 3.44

5.46 ± 4.87

0.0510*

Comp blink (mean ± SD, times/20 s)

5.25 ± 4.32

2.43 ± 2.82

0.0055*

Partial blink (mean ± SD, times/20 s)

2.68 ± 2.76

3.04 ± 3.82

0.6899*

Partial blink ratio (mean ± SD, %)

39.5 ± 38.2

50.3 ± 40.4

0.3055†

  1. BEB Benign essential blepharospasm, DES Dry eye syndrome, SD Standard deviation, LLT Lipid layer thickness, min minimum, Max Maximum, avg Average, MG Meibomian gland, BCVA Best-corrected visual acuity, IOP Intraocular pressure, Comp Complete
  2. *t-test, †chi-square test were used for statistical analyses