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Table 4 Summary of patients with complete remission after treatment

From: Novel prognostic factors and combination therapy outcomes in Morbihan disease: insights from an Asian population

Patients

Age (years)

Gender

Duration of Sx. (months)

Clinical features

Dyslipidemia

Treatment

Treatment time for first response (months)

Treatment time before complete response (months)

1

50s

Man

6

R UL: swelling, erythema, papules, and heating sensation

High LDL and High cholesterol level

Minocycline and tacrolimus for 1 month, partial response

Minocycline, tacrolimus, and ivermectin for 6 months, partial response

Isotretinoin and triamcinolone 2x, complete response

1

16

2

80s

Man

0.5

R UL: swelling and erythema

No

Prednisolone and tacrolimus for 1 month, no response

Minocycline and tacrolimus for 3 months, complete response

1

4

3

60s

Man

3

R UL and LL: swelling, erythema, and heating sensation

No

Minocycline and tacrolimus for 1 month, partial response

Isotretinoin and tacrolimus for 1 month, complete response

1

2

4

60s

Woman

6

L UL and LL: swelling and erythema

High LDL and High cholesterol level

Minocycline and tacrolimus for 1 month, partial response

Minocycline and tacrolimus for 5 months, triamcinolone injection, complete response

3

6

5

50s

Woman

0.5

Bilateral: Facial swelling and erythema

No

Prednisolone and tacrolimus for 1 month, poor response

Minocycline and tacrolimus for 3 months, complete response

1

4

6

60s

Man

1

L UL: swelling, erythema, and heating sensation

No

Prednisolone for 1 month, poor response

Prednisolone and tacrolimus for 2 months, complete response

3

3

7

60s

Man

120

Bilateral UL: swelling and erythema

No

Minocycline, tacrolimus, and ivermectin for 1 month, poor response

Minocycline, tacrolimus, and ivermectin for 11 months, triamcinolone injection 2x, partial response

Isotretinoin for 6 months, complete response

3

14

8

60s

Man

3

R: Facial swelling and erythema

No

Minocycline and tacrolimus for 1 month, poor response

Isotretinoin and tacrolimus for 5 months, triamcinolone injection, partial response

Minocycline, tacrolimus, and ivermectin for 5 months, triamcinolone injection, complete response

3

17

9

60s

Man

3

R UL: swelling and erythema

N/A

Prednisolone for 1 month, poor response

Minocycline and tacrolimus for 5 months, then ivermectin, triamcinolone injection, partial response

Isotretinoin and tacrolimus for 3 months, triamcinolone injection, complete response

2

9

10

50s

Female

3

Bilateral UL and LL: swelling, erythema and papules

No

Isotretinoin and tacrolimus for 1 month, partial response

Isotretinoin and tacrolimus for 3 months, complete response

1

4

  1. Sx symptoms; R right; L left; UL upper lid; LL lower lid; LDL low-density lipid; N/A not available