A single-center analysis of visual outcomes and associated factors after intravenous methylprednisolone treatment for dysthyroid optic neuropathy

Table 6 Multivariable analysis of factors predicting unfavorable outcome to IVMP treatment^a

	Odds Ratio (95% CI)	p-value
Age ≥ 55 years	8.28 (1.368–50.121)	*0.021*
Female sex	2.06 (0.330–12.847)	0.439
Smoking	0.68 (0.120–3.884)	0.666
Poor baseline visual acuity	10.26 (1.363–77.234)	*0.024*
Disc swelling	0.37 (0.071–1.97)	0.246
Proptosis	9.31 (1.872–46.28)	*0.006*
Diabetic mellitus	1.08 (0.225–5.153)	0.926
Onset to treatment time of ≥1 month.	5.10 (1.061–24.501)	*0.042*

^aUnfavorable outcome criteria were considered as < 0.2 improvement in logMAR after 1 week of IVMP. Prognosis-related factors were selected based on a review of the literature. Cut-off for poor baseline visual acuity is logMAR of ≥1. Odds ratios were calculated with the use of multivariable logistic regression model. CI Confidence interval, IVMP Intravenous pulse methylprednisolone, logMAR Logarithm of the minimum angle of resolution. Bold italicized text indicates statistical significance

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