A single-center analysis of visual outcomes and associated factors after intravenous methylprednisolone treatment for dysthyroid optic neuropathy

Table 5 Univariable analysis of factors predicting unfavorable outcome to IVMP treatment^a

Variable	Odds Ratio (95% CI)	p-value
Age ≥ 55 years	2.6 (0.883–7.645)	0.083
Female sex	2.65 (0.61–11.519)	0.193
Smoking	0.66 (0.215–1.989)	0.455
Poor baseline visual acuity	4.11 (0.978–17.229)	0.054
Disc swelling	0.55 (0.175–1.702)	0.296
Proptosis	4.91 (1.574–15.314)	*0.006*
Euthyroid status	0.92 (0.318–2.643)	0.872
Diabetic mellitus	2.63 (0.873–7.893)	0.086
Onset to treatment time of ≥1 month.	1.68 (0.581–4.859)	0.338

^a Unfavorable outcome criteria were considered as < 0.2 improvement in logMAR after 1 week of IVMP. Prognosis-related factors were selected based on a review of the literature. Cut-off for poor baseline visual acuity is logMAR of ≥1. Odds ratios were calculated with the use of logistic regression analysis. Variables with P < 0.5 were included in multivariable model. CI Confidence interval, IVMP Intravenous pulse methylprednisolone, logMAR Logarithm of the minimum angle of resolution. Bold italicized text indicates statistical significance

ISSN: 1471-2415